Tumor associated carbonic anhydrase inhibitors: Rational approaches, design strategies, structure activity relationship and mechanistic insights
The emergence of tumor-associated human carbonic anhydrases (hCA) as promising therapeutic targets has urged rigorous research into the development of potent and selective hCA IX and XII inhibitors. Rationalization of targeting tumor-specific hCA isoforms is a major challenge that requires a compreh...
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Main Authors: | Sridhar Goud Nerella (Author), Pavitra S. Thacker (Author), Mohammed Arifuddin (Author), Claudiu T. Supuran (Author) |
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Format: | Book |
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Elsevier,
2024-04-01T00:00:00Z.
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