Role of estrogen receptor coregulators in endocrine resistant breast cancer

• প্রধান লেখক: Kristin A. Altwegg (লেখক), Ratna K. Vadlamudi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Open Exploration Publishing Inc., 2021-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Breast cancer (BC) is the most ubiquitous cancer in women. Approximately 70-80% of BC diagnoses are positive for estrogen receptor (ER) alpha (ERα). The steroid hormone estrogen [17β-estradiol (E2)] plays a vital role both in the initiation and progression of BC. The E2-ERα mediated actions involve...