Antiribonuclease H2 antibodies are an immune biomarker for systemic lupus erythematosus

• Main Authors: Kazuhisa Nozawa (Author), Kentaro Doe (Author), Kaori Uomori (Author), Iwao Sekigawa (Author), Yoshinari Takasaki (Author), Ken Yamaji (Author), Naoto Tamura (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously reported that autoantibodies against the proliferating cell nuclear antigen protein (PCNA)-binding protein chromatin assembly factor-1 (CAF-1) are specifically found in patients with systemic lupus erythematosus (SLE). PCNA and its complex constituents elicit autoimmune responses in pa...