Antiribonuclease H2 antibodies are an immune biomarker for systemic lupus erythematosus

• Autori principali: Kazuhisa Nozawa (Autore), Kentaro Doe (Autore), Kaori Uomori (Autore), Iwao Sekigawa (Autore), Yoshinari Takasaki (Autore), Ken Yamaji (Autore), Naoto Tamura (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2017-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

We previously reported that autoantibodies against the proliferating cell nuclear antigen protein (PCNA)-binding protein chromatin assembly factor-1 (CAF-1) are specifically found in patients with systemic lupus erythematosus (SLE). PCNA and its complex constituents elicit autoimmune responses in pa...