Multitarget drugs as potential therapeutic agents for alzheimer's disease. A new family of 5-substituted indazole derivatives as cholinergic and BACE1 inhibitors

• Main Authors: Pedro González-Naranjo (Author), Concepción Pérez (Author), Marina González-Sánchez (Author), Adrián Gironda-Martínez (Author), Eugenia Ulzurrun (Author), Fernando Bartolomé (Author), Marcos Rubio-Fernández (Author), Angeles Martin-Requero (Author), Nuria E. Campillo (Author), Juan A. Páez (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multitarget drugs are a promising therapeutic approach against Alzheimer's disease. In this work, a new family of 5-substituted indazole derivatives with a multitarget profile including cholinesterase and BACE1 inhibition is described. Thus, the synthesis and evaluation of a new class of 5-subs...