Engineering attenuated virulence of a Theileria annulata-infected macrophage.

• मुख्य लेखकों: Nadia Echebli (लेखक), Moez Mhadhbi (लेखक), Marie Chaussepied (लेखक), Catherine Vayssettes (लेखक), James P Di Santo (लेखक), Mohamed Aziz Darghouth (लेखक), Gordon Langsley (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Live attenuated vaccines are used to combat tropical theileriosis in North Africa, the Middle East, India, and China. The attenuation process is empirical and occurs only after many months, sometimes years, of in vitro culture of virulent clinical isolates. During this extensive culturing, attenuate...