Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole-In Vitro and In Vivo Investigations

• Váldodahkkit: Nibal Betari (Dahkki), Kristoffer Sahlholm (Dahkki), Xavier Morató (Dahkki), Héctor Godoy-Marín (Dahkki), Olga Jáuregui (Dahkki), Knut Teigen (Dahkki), Francisco Ciruela (Dahkki), Jan Haavik (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Serotonin (5-HT) is a hormone and neurotransmitter that modulates neural activity as well as a wide range of other physiological processes including cardiovascular function, bowel motility, and platelet aggregation. 5-HT synthesis is catalyzed by tryptophan hydroxylase (TPH) which exists as two dist...