Formulation Optimization of Sustained-Release Ammonio Methacrylate Copolymer Microspheres. Effects of Log P and Concentration of Polar Cosolvents, and Role of the Drug/Copolymer Ratio

• Asıl Yazarlar: Piroska Szabó-Révész (Yazar), Klára Pintye-Hódi (Yazar), Péter Sipos (Yazar), István Erős (Yazar), Róbert Rajkó (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2011-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The objectives of this work were the formulation optimization of the preparation process parameters and to evaluate spray-dried sustained-release microspheres using ammonio methacrylate copolymer (AMC) as a polymer matrix. The effects of log P and the concentrations of the cosolvents (acetone, methy...