The Influence of Body Composition on the Systemic Exposure of Paclitaxel in Esophageal Cancer Patients

• Main Authors: Leni van Doorn (Author), Marie-Rose B. S. Crombag (Author), Hánah N. Rier (Author), Jeroen L. A. van Vugt (Author), Charlotte van Kesteren (Author), Sander Bins (Author), Ron H. J. Mathijssen (Author), Mark-David Levin (Author), Stijn L. W. Koolen (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Changes in body composition are associated with chemotherapy-related toxicities and effectiveness of treatment. It is hypothesized that the pharmacokinetics (PK) of chemotherapeutics may depend on body composition. The effects of body composition on the variability of paclitaxel PK were studied in p...