Adenoviral TMBIM6 vector attenuates ER-stress-induced apoptosis in a neonatal hypoxic-ischemic rat model

Adenoviral TMBIM6 vector attenuates ER-stress-induced apoptosis in a neonatal hypoxic-ischemic rat model

Endoplasmic reticulum (ER) stress is a major pathology encountered after hypoxic-ischemic (HI) injury. Accumulation of unfolded proteins triggers the unfolded protein response (UPR), resulting in the activation of pro-apoptotic cascades that lead to cell death. Here, we identified Bax inhibitor 1 (B...

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Main Authors: Desislava Doycheva (Author), Ningbo Xu (Author), Harpreet Kaur (Author), Jay Malaguit (Author), Devin William McBride (Author), Jiping Tang (Author), John H. Zhang (Author)
Format: Book
Published: The Company of Biologists, 2019-11-01T00:00:00Z.
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