Preclinical assessment of drug-drug interaction of fb‐PMT, a novel anti‐cancer thyrointegrin αvβ3 antagonist

• Hoofdauteurs: Kazutoshi Fujioka (Auteur), Mostafa I. Fekry (Auteur), Jeanne M. Rumsey (Auteur), Toni Steiner (Auteur), David Thompson (Auteur), Shaker A. Mousa (Auteur)
• Formaat: Boek
• Gepubliceerd in: Wiley, 2023-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract The objective of the current study was to identify potential drug-drug interactions (DDIs) with the drug candidate fb‐PMT, a novel anticancer thyrointegrin αvß3 antagonist. This was accomplished by using several in vitro assays to study interactions of fb‐PMT with both cytochrome P450 (CYP)...