Effects of TND1128 (a 5-deazaflavin derivative), with self-redox ability, as a mitochondria activator on the mouse brain slice and its comparison with β-NMN

• Hlavní autoři: Nanae Takahashi (Autor), Norio Akaike (Autor), Tomohisa Nagamatsu (Autor), Hiroyuki Uchino (Autor), Yoshihisa Kudo (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2023-02-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

We have no definitive treatment for dementia characterized by prolonged neuronal death due to the enormous accumulation of foreign matter, such as β-amyloid. Since Alzheimer's type dementia develops slowly, we may be able to delay the onset and improve neuronal dysfunction by enhancing the ener...