The Effects of Thymoquinone on Viability, and Anti-apoptotic Factors (BCL-XL, BCL-2, MCL-1) in Prostate Cancer (PC3) Cells: An In Vitro and Computer-Simulated Environment Study

• Auteurs principaux: Javad Saffari_Chaleshtori (Auteur), Ehsan Heidari-Sureshjani (Auteur), Fahimeh Moradi (Auteur), Esfandiar Heidarian (Auteur)
• Format: Livre
• Publié: Tabriz University of Medical Sciences, 2019-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Purpose: Since active plant ingredients can induce apoptosis in many tumors, in this study we evaluate the apoptotic effects of thymoquinone (TQ) on PC3 cells. Also, we predicted the interaction of TQ with BCL-XL, BCL-2, and MCL-1anti-apoptotic factors by computer-simulated environment. Methods: PC3...