Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission

Divisions at the periphery and midzone of mitochondria are two fission signatures that determine the fate of mitochondria and cells. Pharmacological induction of excessively asymmetric mitofission-associated cell death (MFAD) by switching the scission position from the mitochondrial midzone to the p...

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Main Authors: Xiao-Ling Liang (Author), Lan Ouyang (Author), Nan-Nan Yu (Author), Zheng-Hua Sun (Author), Zi-Kang Gui (Author), Yu-Long Niu (Author), Qing-Yu He (Author), Jing Zhang (Author), Yang Wang (Author)
Format: Knjiga
Izdano: Elsevier, 2023-10-01T00:00:00Z.
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