Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals

• Glavni autori: Francisco Castillo (Autor), David Ramírez (Autor), María C. Ramos (Autor), Blanca Martinez-Arribas (Autor), Elisabeth Domingo-Contreras (Autor), Thomas A. Mackenzie (Autor), Carlos Peña-Varas (Autor), Sven Lindemann (Autor), Fernando Montero (Autor), Fredderick Annang (Autor), Francisca Vicente (Autor), Olga Genilloud (Autor), Dolores González-Pacanowska (Autor), Rosario Fernandez-Godino (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The SARS coronavirus 2 (SARS-CoV-2) epidemic remains globally active. The emergence of new variants of interest and variants of concern (VoCs), which are potentially more vaccine-resistant and less sensitive to existing treatments, is evident due to their high prevalence. The prospective spread of s...