Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals

• Main Authors: Francisco Castillo (Author), David Ramírez (Author), María C. Ramos (Author), Blanca Martinez-Arribas (Author), Elisabeth Domingo-Contreras (Author), Thomas A. Mackenzie (Author), Carlos Peña-Varas (Author), Sven Lindemann (Author), Fernando Montero (Author), Fredderick Annang (Author), Francisca Vicente (Author), Olga Genilloud (Author), Dolores González-Pacanowska (Author), Rosario Fernandez-Godino (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The SARS coronavirus 2 (SARS-CoV-2) epidemic remains globally active. The emergence of new variants of interest and variants of concern (VoCs), which are potentially more vaccine-resistant and less sensitive to existing treatments, is evident due to their high prevalence. The prospective spread of s...