Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals

• Автори: Francisco Castillo (Автор), David Ramírez (Автор), María C. Ramos (Автор), Blanca Martinez-Arribas (Автор), Elisabeth Domingo-Contreras (Автор), Thomas A. Mackenzie (Автор), Carlos Peña-Varas (Автор), Sven Lindemann (Автор), Fernando Montero (Автор), Fredderick Annang (Автор), Francisca Vicente (Автор), Olga Genilloud (Автор), Dolores González-Pacanowska (Автор), Rosario Fernandez-Godino (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The SARS coronavirus 2 (SARS-CoV-2) epidemic remains globally active. The emergence of new variants of interest and variants of concern (VoCs), which are potentially more vaccine-resistant and less sensitive to existing treatments, is evident due to their high prevalence. The prospective spread of s...