In Vitro & In Vivo Studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of <i>Rana chensinensis</i> as the Optimised Antibacterial Prototype Drug

• Main Authors: Zhuming Ye (Author), Xiaowei Zhou (Author), Xinping Xi (Author), Yu Zai (Author), Mei Zhou (Author), Xiaoling Chen (Author), Chengbang Ma (Author), Tianbao Chen (Author), Lei Wang (Author), Hang Fai Kwok (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amphibian skin secretion is an ideal source of antimicrobial peptides that are difficult to induce drug resistance to due to their membrane-targeting mechanism as a new treatment scheme. In this study, a natural antimicrobial peptide Temporin-1CEh was identified by molecular cloning and mass spectro...