Celastrol-regulated gut microbiota and bile acid metabolism alleviate hepatocellular carcinoma proliferation by regulating the interaction between FXR and RXRα in vivo and in vitro

Celastrol, a triterpene derived from Thunder God Vine (Tripterygium wilfordii Hook f; Celastraceae), a traditional Chinese herb, has promising anticancer activity. The present study aimed to elucidate an indirect mechanism of celastrol-mediated alleviation of hepatocellular carcinoma (HCC) via gut m...

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Main Authors: Dequan Zeng (Author), Lipen Zhang (Author), Qiang Luo (Author)
Format: Book
Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
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3rd Floor Main Library

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