The expanding spectrum of neurological disorders of phosphoinositide metabolism

• Main Authors: Jonathan R. Volpatti (Author), Almundher Al-Maawali (Author), Lindsay Smith (Author), Aqeela Al-Hashim (Author), Julie A. Brill (Author), James J. Dowling (Author)
• Format: Book
• Published: The Company of Biologists, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phosphoinositides (PIPs) are a ubiquitous group of seven low-abundance phospholipids that play a crucial role in defining localized membrane properties and that regulate myriad cellular processes, including cytoskeletal remodeling, cell signaling cascades, ion channel activity and membrane traffic....