Oxidative Stress Boosts the Uptake of Cerium Oxide Nanoparticles by Changing Brain Endothelium Microvilli Pattern

• Main Authors: Roberta Dal Magro (Author), Agostina Vitali (Author), Stefano Fagioli (Author), Alberto Casu (Author), Andrea Falqui (Author), Beatrice Formicola (Author), Lorenzo Taiarol (Author), Valeria Cassina (Author), Claudia Adriana Marrano (Author), Francesco Mantegazza (Author), Umberto Anselmi-Tamburini (Author), Patrizia Sommi (Author), Francesca Re (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vascular oxidative stress is considered a worsening factor in the progression of Alzheimer's disease (AD). Increased reactive oxygen species (ROS) levels promote the accumulation of amyloid-β peptide (Aβ), one of the main hallmarks of AD. In turn, Aβ is a potent inducer of oxidative stress. In...