Overexpression of Dehydrogenase/Reductase 9 Predicts Poor Response to Concurrent Chemoradiotherapy and Poor Prognosis in Rectal Cancer Patients

• Main Authors: Tzu-Ju Chen (Author), Bei-Hao Hsu (Author), Sung-Wei Lee (Author), Ching-Chieh Yang (Author), Yu-Feng Tian (Author), Yu-Hsuan Kuo (Author), Wan-Shan Li (Author), Hsin-Hwa Tsai (Author), Li-Ching Wu (Author), Cheng-Fa Yeh (Author), Chia-Lin Chou (Author), Hong-Yue Lai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To reduce the risk of locoregional recurrence, the addition of neoadjuvant concurrent chemoradiotherapy (CCRT) is recommended before surgical management for rectal cancer patients. However, despite identical tumor histology, individual patient response to neoadjuvant CCRT varies greatly....