A Novel Indolizine Derivative Induces Apoptosis Through the Mitochondria p53 Pathway in HepG2 Cells

• Autori principali: Yushuang Liu (Autore), Enxian Shao (Autore), Zhiyang Zhang (Autore), Daji Yang (Autore), Guanting Li (Autore), Hua Cao (Autore), Hongliang Huang (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Indolizine derivatives are a class of compounds with excellent biological activity. In this study, a series of indolizine derivatives, compound 1 (C1), compound 2 (C2), compound 3 (C3), and compound 4 (C4), were synthesized. 3-(4,5-dimethylthiazole)-2,5-diphenyltetraazolium bromide (MTT) assay was u...