Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy

• Main Authors: Xiuxiu Jiao (Author), Yuan Yu (Author), Jianxia Meng (Author), Mei He (Author), Charles Jian Zhang (Author), Wenqian Geng (Author), Baoyue Ding (Author), Zhuo Wang (Author), Xueying Ding (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dbait is a small double-stranded DNA molecule that has been utilized as a radiosensitizer to enhance the sensitivity of glioma to radiotherapy (RT). However, there is no effective drug delivery system to effectively overcome the bloodbrain barrier (BBB). The aim of this study was to develop a gene...