Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice

• 主要な著者: Shuang Liu (著者), Xing Wen (著者), Qihan Huang (著者), Minghui Zhu (著者), Jun Lu (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Cisplatin is one of the most active chemotherapy drugs to treat solid tumors. However, it also causes various side effects, especially nephrotoxicity, in which oxidative stress plays critical roles. Our previous studies found that cisplatin selectively inhibited selenoenzyme thioredoxin reductase1 (...