Crystalline silica activates the T-cell and the B-cell antigen receptor complexes and induces T-cell and B-cell proliferation

• Main Authors: Theodoros Eleftheriadis (Author), Georgios Pissas (Author), Sotirios Zarogiannis (Author), Vassilios Liakopoulos (Author), Ioannis Stefanidis (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Silicosis is an occupational fibrotic lung disease, which is associated with an increased incidence of autoimmune diseases. The effect of crystalline silica on the immune system is thought to be mediated by the antigen presenting cells. However, the direct effect of silica on T-cells and B-cells has...