PR3-ANCA in Wegener's granulomatosis prime human mononuclear cells for enhanced activation via TLRs and NOD1/2

• Main Authors: Iwashiro Atsushi (Author), Sato Tadasu (Author), Uehara Akiko (Author), Yokota Sou (Author)
• פורמט: ספר
• יצא לאור: BMC, 2009-07-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Anti-neutrophil cytoplasmic antibodies (ANCA) is autoantibodies characteristic of vasculitis diseases. A connection between ANCA and Wegener's granulomatosis was well established. The interaction of both ANCA phenotypes (PR3-ANC...