Successful Treatment of Drug-Resistant Seizures Secondary to Ring 20 Mosaicism with Perampanel as an Add-On Antiepileptic Drug

• Main Authors: Janet Ling (Author), Wai Lan Yeung (Author), Kam Lun Hon (Author), Ivan F. M. Lo (Author), Ho-Ming Luk (Author), Cheuk Wing Fung (Author), Alexander K. C. Leung (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We report a girl with drug-resistant seizures, progressive behavioral changes, and cognitive decline. Investigations showed abnormal EEG with frequent high-voltage bifrontotemporal sharp and slow waves, especially during sleep. Seizures were difficult to control, despite the usage of various antiepi...