The E3 ligase TRIM56 is a host restriction factor of Zika virus and depends on its RNA-binding activity but not miRNA regulation, for antiviral function.

• Päätekijät: Darong Yang (Tekijä), Nan L Li (Tekijä), Dahai Wei (Tekijä), Baoming Liu (Tekijä), Fang Guo (Tekijä), Husni Elbahesh (Tekijä), Yunzhi Zhang (Tekijä), Zhi Zhou (Tekijä), Guo-Yun Chen (Tekijä), Kui Li (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Public Library of Science (PLoS), 2019-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Infection by Zika virus (ZIKV) is linked to microcephaly and other neurological disorders, posing a significant health threat. Innate immunity is the first line of defense against invading pathogens, but relatively little is understood regarding host intrinsic mechanisms that guard against ZIKV. Her...