Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice

• Autores principales: Yu-Hui Gu (Autor), Kai-Wen Ren (Autor), Yu Wang (Autor), Shi-Hao Wang (Autor), Xiao-Hong Yu (Autor), Li-Wen Xu (Autor), Hui-Hua Li (Autor), Hai-Lian Bi (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Hypertension is one of the common causes of pathological cardiac hypertrophy and a major risk for morbidity and mortality of cardiovascular diseases worldwide. Ubiquitin-Specific Protease 7 (USP7), the first identified deubiquitinating enzymes, participated in a variety of biological processes, such...