Biodistribution of the saponin-based adjuvant Matrix-M™ following intramuscular injection in mice

• Главные авторы: Cecilia Carnrot (Автор), Berit Carow (Автор), Anna-Karin E. Palm (Автор), Eray Akpinar (Автор), Per-Henrik Helgesson (Автор), Ingrid Lekberg Osterman (Автор), Emelie Bringeland (Автор), Bryant Foreman (Автор), Nita Patel (Автор), Johan Bankefors (Автор), Louis Fries (Автор), Linda Stertman (Автор)
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• Опубликовано: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Предметы: article
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Novel adjuvants are extensively utilized in the development of safe and effective vaccines against emerging pathogens. Matrix-M™ adjuvant is a saponin-based adjuvant used in several active clinical development programs and in widespread use in the COVID-19 vaccine NVX-CoV2373. Here, we conducted a b...