Sustained Analgesic Effect of the Rho Kinase Inhibitor AS1892802 in Rat Models of Chronic Pain

To assess the pharmacological profile of AS1892802, a novel and selective Rho kinase (ROCK) inhibitor, we examined the effects of repeated dosing with AS1892802 on models of monoiodoacetate-induced arthritis and streptozotocin-induced neuropathy. Although single dosing of AS1892802 exerted a short-a...

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Main Authors: Eiji Yoshimi (Author), Hiroko Yamamoto (Author), Yasuhisa Furuichi (Author), Yasuaki Shimizu (Author), Nobuaki Takeshita (Author)
Format: Book
Published: Elsevier, 2010-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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