Comparative assessment of ELISAs using recombinant saposin-like protein 2 and recombinant cathepsin L-1 from Fasciola hepatica for the serodiagnosis of human Fasciolosis.

• Main Authors: Bruno Gottstein (Author), Marianne Schneeberger (Author), Ghalia Boubaker (Author), Bernadette Merkle (Author), Cristina Huber (Author), Markus Spiliotis (Author), Norbert Müller (Author), Teresa Garate (Author), Marcus G Doherr (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Two recombinant Fasciola hepatica antigens, saposin-like protein-2 (recSAP2) and cathepsin L-1 (recCL1), were assessed individually and in combination in enzyme-linked immunosorbent assays (ELISA) for the specific serodiagnosis of human fasciolosis in areas of low endemicity as encountered in Centra...