Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells.

• 主要な著者: Ross A Paveley (著者), Sarah A Aynsley (著者), Peter C Cook (著者), Joseph D Turner (著者), Adrian P Mountford (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2009-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Infection of the mammalian host by the parasitic helminth Schistosoma mansoni is accompanied by the release of excretory/secretory molecules (ES) from cercariae which aid penetration of the skin. These ES molecules are potent stimulants of innate immune cells leading to activation of acquired immuni...