Molecular Modeling Applied to the Discovery of New Lead Compounds for P2 Receptors Based on Natural Sources

• Main Authors: Anael Viana Pinto Alberto (Author), Natiele Carla da Silva Ferreira (Author), Rafael Ferreira Soares (Author), Luiz Anastacio Alves (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

P2 receptors are a family of transmembrane receptors activated by nucleotides and nucleosides. Two classes have been described in mammals, P2X and P2Y, which are implicated in various diseases. Currently, only P2Y12 has medicines approved for clinical use as antiplatelet agents and natural products...