TLR2-Dependent Signaling for IL-15 Production Is Essential for the Homeostasis of Intestinal Intraepithelial Lymphocytes

• Main Authors: Yuan Qiu (Author), Aimin Pu (Author), Hong Zheng (Author), Minqiang Liu (Author), Weigang Chen (Author), Wensheng Wang (Author), Weidong Xiao (Author), Hua Yang (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

TLR2 signaling is related to colitis and involved in regulation of innate immunity in the intestinal tract, but the mechanisms remain unclear. The aim of this study is to investigate how TLR2 affects differentiation of intraepithelial lymphocytes (IELs) and regulates the susceptibility of colitis. I...