Human Leukocyte Antigen Class II Alleles (DQB1 and DRB1) as Predictors for Response to Interferon Therapy in HCV Genotype 4

• Main Authors: Olfat Shaker (Author), Heba Bassiony (Author), Maissa El Raziky (Author), Samer S. El-Kamary (Author), Gamal Esmat (Author), Akmal M. El-Ghor (Author), Mona M. Mohamed (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human leukocyte antigens class II play an important role in immune response against HCV. We investigated whether HLA class II alleles influence susceptibility to HCV infection and response to interferon therapy. HLA-DRB1 and -DQB1 loci were genotyped using PCR-SSO Luminex technology. According to ou...