Impact of CYP2C19 polymorphisms on serum concentration of voriconazole in iranian hematological patients

• Main Authors: Sholeh Ebrahimpour (Author), Soha Namazi (Author), Mehdi Mohammadi (Author), Mohsen Nikbakht (Author), Molouk Hadjibabaie (Author), Hamidreza Taghvaye Masoumi (Author), Ardeshir Ghavamzadeh (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study aimed to determine the portion of Iranian patients who attain therapeutic serum concentrations of voriconazole (VRCZ) following administration of fixed doses. In addition, the effect of CYP2C19 polymorphism on serum levels of VRCZ was also investigated. Methods: Forty-eight adu...