Mechanism of Paeoniflorin in the Treatment of Bile Duct Ligation-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology

• मुख्य लेखकों: Shizhang Wei (लेखक), Xiao Ma (लेखक), Ming Niu (लेखक), Ruilin Wang (लेखक), Tao Yang (लेखक), Dan Wang (लेखक), Jianxia Wen (लेखक), Haotian Li (लेखक), Yanling Zhao (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Paeoniflorin (PF) is the main active component of Paeonia lactiflora Pall., which is used in the treatment of severe cholestatic hepatitis. However, its biological mechanism in regulating bile acid metabolism and cholestatic liver injury has not been fully revealed. Our study aimed to reveal the mec...