Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function

• Үндсэн зохиолчид: Rumeng Yao (Зохиогч), Ruiyuan Pan (Зохиогч), Chao Shang (Зохиогч), Xiaoheng Li (Зохиогч), Jinbo Cheng (Зохиогч), Jiangping Xu (Зохиогч), Yunfeng Li (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

TSPO is mainly expressed in the mitochondrial outer membrane of microglia in the central nervous system, and its expression is greatly increased when microglia are activated. However, the role and mechanism of this protein in microglial activation is not well characterized. In this study, we investi...