Actin Alpha 2 (ACTA2) Downregulation Inhibits Neural Stem Cell Migration through Rho GTPase Activation

• Main Authors: Ji Zhang (Author), Xuheng Jiang (Author), Chao Zhang (Author), Jun Zhong (Author), Xuanyu Fang (Author), Huanhuan Li (Author), Fangke Xie (Author), Xiaofei Huang (Author), Xiaojun Zhang (Author), Quan Hu (Author), Hongfei Ge (Author), Anyong Yu (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although neural stem cells (NSCs) could migrate towards lesions after central nervous system (CNS) injury, the migration ability always is restricted due to the disturbed composition and density of the adhesion ligands and extracellular matrix (ECM) gradient after CNS injury. To date, various method...