Dosage Strategy of Linezolid According to the Trough Concentration Target and Renal Function in Chinese Critically Ill Patients

• Main Authors: Fan Wu (Author), Xiao-Shan Zhang (Author), Ying Dai (Author), Zi-Ye Zhou (Author), Chun-Hong Zhang (Author), Lu Han (Author), Fang-Min Xu (Author), Ye-Xuan Wang (Author), Da-Wei Shi (Author), Guan-Yang Lin (Author), Xu-Ben Yu (Author), Fang Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Linezolid is associated with myelosuppression, which may cause failure in optimally treating bacterial infections. The study aimed to define the pharmacokinetic/toxicodynamic (PK/TD) threshold for critically ill patients and to identify a dosing strategy for critically ill patients with...