A randomized, double‐blind, placebo‐ and positive‐controlled crossover study of the effects of durlobactam on cardiac repolarization in healthy subjects

• Glavni autori: John O'Donnell (Autor), Kathleen Maloney (Autor), Melissa Steidler (Autor), Royce Morrison (Autor), Robin Isaacs (Autor)
• Format: Knjiga
• Izdano: Wiley, 2021-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Durlobactam (formerly ETX2514) is a diazabicyclooctane β‐lactamase inhibitor that inhibits class A, C, and D β‐lactamases. Sulbactam combined with durlobactam has in vitro and in vivo activity against Acinetobacter baumannii including carbapenem‐ and colistin‐resistant isolates and is being...