Sensitive detection of microRNAs using polyadenine-mediated fluorescent spherical nucleic acids and a microfluidic electrokinetic signal amplification chip

• Main Authors: Jun Xu (Author), Qing Tang (Author), Runhui Zhang (Author), Haoyi Chen (Author), Bee Luan Khoo (Author), Xinguo Zhang (Author), Yue Chen (Author), Hong Yan (Author), Jincheng Li (Author), Huaze Shao (Author), Lihong Liu (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The identification of tumor-related microRNAs (miRNAs) exhibits excellent promise for the early diagnosis of cancer and other bioanalytical applications. Therefore, we developed a sensitive and efficient biosensor using polyadenine (polyA)-mediated fluorescent spherical nucleic acid (FSNA) for miRNA...