Effect of Empagliflozin on Thioacetamide-Induced Liver Injury in Rats: Role of AMPK/SIRT-1/HIF-1α Pathway in Halting Liver Fibrosis

Effect of Empagliflozin on Thioacetamide-Induced Liver Injury in Rats: Role of AMPK/SIRT-1/HIF-1α Pathway in Halting Liver Fibrosis

Hepatic fibrosis causes severe morbidity and death. No viable treatment can repair fibrosis and protect the liver until now. We intended to discover the empagliflozin's (EMPA) hepatoprotective efficacy in thioacetamide (TAA)-induced hepatotoxicity by targeting AMPK/SIRT-1 activity and reducing...

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Main Authors: Marwan A. ElBaset (Author), Rana S. Salem (Author), Fairouz Ayman (Author), Nadeen Ayman (Author), Nooran Shaban (Author), Sherif M. Afifi (Author), Tuba Esatbeyoglu (Author), Mahmoud Abdelaziz (Author), Zahraa S. Elalfy (Author)
Format: Book
Published: MDPI AG, 2022-10-01T00:00:00Z.
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