Anti-CD123 antibody-modified niosomes for targeted delivery of daunorubicin against acute myeloid leukemia

• Main Authors: Fu-rong Liu (Author), Hui Jin (Author), Yin Wang (Author), Chen Chen (Author), Ming Li (Author), Sheng-jun Mao (Author), Qiantao Wang (Author), Hui Li (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A novel niosomal delivery system was designed and investigated for the targeted delivery of daunorubicin (DNR) against acute myeloid leukemia (AML). Anti-CD123 antibodies conjugated to Mal-PEG2000-DSPE were incorporated into normal niosomes (NS) via a post insertion method to afford antibody-modifie...