Simulating Sleep Apnea by Exposure to Intermittent Hypoxia Induces Inflammation in the Lung and Liver

• Main Authors: Darlan Pase da Rosa (Author), Luiz Felipe Forgiarini (Author), Diego Baronio (Author), Cristiano Andrade Feijó (Author), Dênis Martinez (Author), Norma Possa Marroni (Author)
• Format: Book
• Published: Hindawi Limited, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sleep apnea is a breathing disorder that results from momentary and cyclic collapse of the upper airway, leading to intermittent hypoxia (IH). IH can lead to the formation of free radicals that increase oxidative stress, and this mechanism may explain the association between central sleep apnea and...