A physiologically based pharmacokinetic model for V937 oncolytic virus in mice

Introduction: Oncolytic viruses (OVs) represent a novel therapeutic strategy in oncology due to their capability to selectively infect and replicate in cancer cells, triggering a direct and/or immune-induced tumor lysis. However, the mechanisms governing OV pharmacokinetics are still poorly understo...

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Main Authors: Sara Peribañez-Dominguez (Author), Zinnia P. Parra-Guillen (Author), Tomoko Freshwater (Author), Iñaki F. Troconiz (Author)
Format: Book
Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
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