A physiologically based pharmacokinetic model for V937 oncolytic virus in mice
Introduction: Oncolytic viruses (OVs) represent a novel therapeutic strategy in oncology due to their capability to selectively infect and replicate in cancer cells, triggering a direct and/or immune-induced tumor lysis. However, the mechanisms governing OV pharmacokinetics are still poorly understo...
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Frontiers Media S.A.,
2023-09-01T00:00:00Z.
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