A physiologically based pharmacokinetic model for V937 oncolytic virus in mice

• Asıl Yazarlar: Sara Peribañez-Dominguez (Yazar), Zinnia P. Parra-Guillen (Yazar), Tomoko Freshwater (Yazar), Iñaki F. Troconiz (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Introduction: Oncolytic viruses (OVs) represent a novel therapeutic strategy in oncology due to their capability to selectively infect and replicate in cancer cells, triggering a direct and/or immune-induced tumor lysis. However, the mechanisms governing OV pharmacokinetics are still poorly understo...