Focused ultrasound-mediated small-molecule delivery to potentiate immune checkpoint blockade in solid tumors

• Main Authors: Qiuyu Wu (Author), Yuanhang Xia (Author), Xiaohe Xiong (Author), Xinxing Duan (Author), Xiaoxiao Pang (Author), Fugui Zhang (Author), Song Tang (Author), Junlei Su (Author), Shuqiong Wen (Author), Li Mei (Author), Richard D. Cannon (Author), Ping Ji (Author), Zhanpeng Ou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the last decade, immune checkpoint blockade (ICB) has revolutionized the standard of treatment for solid tumors. Despite success in several immunogenic tumor types evidenced by improved survival, ICB remains largely unresponsive, especially in "cold tumors" with poor lymphocyte infiltra...