1,25-Dihydroxyvitamin D inhibits hepatic diacyglycerol accumulation and ameliorates metabolic dysfunction in polycystic ovary syndrome rat models

• Main Authors: Xin Yuan (Author), Jianshu Yang (Author), Danlin Sun (Author), Kaiming Luo (Author), Xiaohong Jiang (Author), Long Wang (Author), Shoukui Xiang (Author), Yijie Jiang (Author), Kele Ge (Author), Zhiyang Zhou (Author), Bowen Li (Author), Fei Hua (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: We aimed to evaluate the influence of 1,25-dihydroxyvitamin D (1,25(OH)2D) on metabolic dysfunction and elucidate its underlying mechanism using a rat model of polycystic ovary syndrome (PCOS).Methods: Twenty-four Sprague-Dawley rats were randomly divided into four groups: control grou...