Development of a novel, single-cycle replicable rift valley Fever vaccine.

• Main Authors: Shin Murakami (Author), Kaori Terasaki (Author), Sydney I Ramirez (Author), John C Morrill (Author), Shinji Makino (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) is an arbovirus that causes severe disease in humans and livestock in sub-Saharan African countries. Although the MP-12 strain of RVFV is a live attenuated vaccine candidate, neuroinvasiveness and neurovirulence of MP-12 in mice...