Bayesian Modeling Immune Reconstitution Apply to CD34+ Selected Stem Cell Transplantation for Severe Combined Immunodeficiency

• Main Authors: Jean-Sebastien Diana (Author), Naïm Bouazza (Author), Chloe Couzin (Author), Martin Castelle (Author), Alessandra Magnani (Author), Elisa Magrin (Author), Jeremie Rosain (Author), Jean-Marc Treluyer (Author), Capucine Picard (Author), Despina Moshous (Author), Stéphane Blanche (Author), Bénédicte Neven (Author), Marina Cavazzana (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe combined immunodeficiencies (SCIDs) correspond to the most severe form of primary immunodeficiency. Allogeneic hematopoietic stem cell transplantation (HSCT) and gene therapy are curative treatments, depending on the donor's availability and molecular diagnostics. A partially human leuko...