Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection.

• Main Authors: Dulharie T Wijeratne (Author), Samitha Fernando (Author), Laksiri Gomes (Author), Chandima Jeewandara (Author), Anushka Ginneliya (Author), Supun Samarasekara (Author), Ananda Wijewickrama (Author), Clare S Hardman (Author), Graham S Ogg (Author), Gathsaurie Neelika Malavige (Author)
• Format: Bog
• Udgivet: Public Library of Science (PLoS), 2018-10-01T00:00:00Z.
• Fag: article
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<h4>Background</h4>In order to understand the role of dengue virus (DENV) specific T cell responses that associate with protection, we studied their frequency and phenotype in relation to clinical disease severity and resolution of viraemia in a large cohort of patients with varying seve...